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Coordination activities will be developed to achieve the following main goals: 1. foster cross-fertilization between the four different scientific areas on which this project focuses, mainly through the common vertical aspects; 2. contribute to the development and dissemination of common good practices and methodological approaches; 3. foster the transfer of knowledge among different research teams, thereby enhancing the spreading of innovative methods and tools; 4. implement a common reference point for the European NMR community in the internet, by maintaining a common virtual laboratory; 5. jointly identify bottlenecks and possible breakthroughs in the field of biological NMR. The project is divided in the following workpackages (WP): WP0: Project coordination WP1: Protein-protein interactions WP2: Protein-DNA/RNA interactions WP3: Protein-ligand interactions WP4: Membrane and immobilized proteins WP5: Virtual laboratory WP0 is devoted to project management. WP1-4 are developed in parallel and involve similar actions in the four scientific areas (protein-protein interactions; protein-DNA/RNA interactions; protein-ligand interactions; membrane and immobilized proteins) addressed by the project. The fifth WP is concerned with the implementation and maintenance of the present web site, acting as a common virtual laboratory, as well as with the preparation and diffusion of a periodic newsletter, dissemination of documents and results of studies.